A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 1 and neuraminidase 2. Epidemiology.
The H1 protein of the H1N2 virus is like the H1 protein of the currently circulating H1N1 viruses and the N2 protein is similar to the N2 protein in the currently circulating H3N2 viruses. It was found that 99.6% of the samples were resistant to oseltamivir while none were resistant to zanamivir.
[12] Retrospective serologic testing subsequently demonstrated that up to 230 soldiers had been infected with the novel virus, which was an H1N1 strain. [39] It has been suggested that pregnant women and certain populations such as native North Americans have a greater likelihood of developing a T helper type 2 response to H1N1 influenza which may be responsible for the systemic inflammatory response syndrome that causes pulmonary edema and death. Well known outbreaks of H1N1 strains in humans include the 2009 swine flu pandemic, as well as the 1918 flu pandemic. [29] [40], On 26 April 2011, an H1N1 pandemic preparedness alert was issued by the World Health Organization for the Americas.
It is endemic in both human and pig populations.
This leads to extensive leukocyte migration towards the lungs, resulting in the destruction of lung cells and secretion of blood and mucus into the alveoli and airways.
H3N2 is one subtype of the influenza virus that often causes significant illness. [50][51], Maldives reported swine flu in early 2017;[52][better source needed] 501 people were tested for the disease and 185 (37%) of those tested were positive for the disease. Janet Daly, Japhette E. Kembou-Ringert, in Reference Module in Life Sciences, 2019. Between December 1988 and March 1989, 19 influenza H1N2 virus isolates were identified in 6 cities in China, but the virus did not spread further.[1]. The virus was included in the 1978–79 influenza vaccine.[18][19][20][21]. Because the hemagglutinin protein of the virus is similar to that of the currently[when?] Web. [78], Pregnant women who become infected with the influenza are advised to contact their doctor immediately.
Patient Zero was never identified. circulating A(H1N1) viruses and the neuraminidase protein is similar to that of the current A(H3N2) viruses, the seasonal flu vaccine should provide good protection against influenza virus as well as protection against the currently circulating seasonal A(H1N1), A(H3N2), and B viruses.
[81] Both amantadine and rimantadine have been found to be teratogenic and embryotoxic (malformations and toxic effects on the embryo) when given at high doses in animal studies. [65] The virus is a variant genotype 4 (G4) Eurasian avian-like (EA) H1N1 virus that mainly affects pigs, but there is some evidence of it infecting people. "[66], Michael Ryan, executive director of the World Health Organization (WHO) Health Emergencies Program, stated in July 2020 that this strain of influenza virus was not new and had been under surveillance since 2011.
The virus does not cause more severe illness than other influenza viruses, and no unusual increases in influenza activity have been associated with it. Meaning of influenza a virus, h1n2 subtype. Three major subtypes of IAV circulate in the pig population worldwide.
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