Spawns another Vurp! Displays additional information like item type, charges, transformations, Spindown Dice results, Bag of Crafting recipes, TMTRAINER item effects (Detailed informations require --luadebug flag! You may take only one of the items, before being teleported back to where you were, It's literally every item, that includes items not in item pools like Knife Pieces, UNLOCK: Unlock this item by completing every post-it note for every character, including the Tainted characters, Gives you a robot fly familar that orbits around Isaac and fires shielded tears at incoming projectiles, Deals contact damage to enemies it touches, Item Pool: Item Room, Key Beggar, Crane Game, When used, the Meat Cleaver will split all enemies in the room into 2 smaller versions with ~40% health each, For enemies that have multiple parts to them (e.g. Doing so will cause it to increase in size, and also increase their damage and the damage of the burst tears, Once a tear is fed 5 times, it will immediately burst, Tears in the burst will deal half the damage the main tear would have, Added as part of the Afterbirth+ Booster Pack #4. achievement (complete a victory lap, defeating the lamb boss), Horf! Isaac doesn't take damage from this effect, UNLOCK: Unlock this item by defeating Delirium as Tainted Lost, Spawns a familiar that's attached via an Umbilical Cord, but will move and shoot in the same direction Isaac is shooting, When activated you first need to throw the familiar, which deals x3 your tear damage to any enemies it touches, Gello's tears deal x0.75 your tear damage (x1.0 if Lilith), Can be used multiple times per room to spawn more familiars, however they only last for the current room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lilith, When used, this item allows you to throw your head where it will sit as a stationary sentry firing bullets until you walk over and pick it up again, Throwing Isaac's head deals 24 damage to anything it hits while being thrown, Your hitbox remains with the body. in a small boss room), UNLOCK: Unlock this item by defeating Greedier Mode with Lilith, Gives you a 100% chance to find an Angel Room on every valid floor after defeating the boss, Doesn't spawn an angel room on any floor where it is normally not possible to find one (e.g. item room pool, question mark book, white, When used, spawns 4-8 friendly blue spiders on the floor, REPENTANCE - Used to give 1-4 spiders per use, * item room, treasure room, item room poolgrey, gray, Allows you to fire a red flame infront of you, similar to the Blue Candle item, however the flame will stay 10 seconds, Each flame deals 125 total damage before it disappears, The flame will shrink in size when deals damage to something and eventually disappear, REPENTANCE - Red Candle flames now time out after ten seconds and automatically extinguish. Suicide King or using The Bible on Isaac, ??? Fire Dips burn enemies and leave a fire behind on death, UNLOCK: Unlock this item by defeating challenge #36 (Scat Man), When used, places a sword directly above Isaac's head and while active, will spawn an extra item for every item pedestal spawned, After getting hit once with the item activated, at any time without warning, the sword may fall, instantly killing Isaac regardless of his health, After being hit the sword has a 1/10000 chance every 4 frames to fall. If your speed stat is already higher then that value is still used, Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack The Sky. Replacing all 12 containers with broken hearts will kill you instantly. shop room pool, shop item pool, cross, brown, Upon use, gives +2 damage up which lasts for the current room, x1.5 times Damage Multiplier if you also have Blood of the Martyr (Does not stack with Magic Mushroom or Cricket's Head multipliers), Increases your chances of getting a devil/angel room by +12.5%, REPENTANCE - The effect stacks if used multiple times, * library pool, library room, book room pool, devil pool, devil room pool, devil deal, starting debug 5 - Displays text at the bottom of the screen about the current room. * shop room pool, shop item pool, the lost item pool, white, Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick, BFFs will cause the Guillotine head to do double damage (14 damage per tick), Tears are still fired from Isaac's head but the hitbox remains around his body, UNLOCK: Unlock this item by beating the Isaac boss with Judas, * item room, treasure room, item room pool, chop, head, silver, metal, Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick and blocks enemy shots, Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies, Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears, A fourth Ball of Bandages will make the Bandage Girl bigger and stronger, making her deal 5.5 damage per tick instead, Any further Ball of Bandages will repeat the cycle, Increases the chance of champion enemies appearing by 15%, Doesn't affect the chance for champion bosses to spawn, * shop room pool, shop item pool, red, croissant, crescent, Bombs now become poop bombs, which deal 10 damage to all enemies in the room and daze them for a short period of time, Butt Bombs heal the poop bosses (Dingle, Dangle, Brownie) by 25% of their max HP, * boss rush pool, boss rush room, item room, treasure room, item room pool, poop, face, brown, If Isaac stands still and stops shooting for a second, he turns to stone, making him invincible until he moves/shoots again, Using bombs or your active item will remove the invicibility as well, This item is a reference to the Tanuki suit in Super Mario 3, * item room, treasure room, item room pool, raccoon, green, Spawns 2-5 friendly attack spiders every time you take damage, REPENTANCE - Buffed, used to spawn 1-2 spiders, * item room, treasure room, item room pool, the lost item pool, purple, blue, heart, cute spider baby, When Isaac dies, he has a 50% chance to resurrect with 1/2 a heart, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, However, If you also have flying you will always take damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, bomb, A random chance when you take damage to get an invincibility shield for 7 seconds, The chance to get an invincibility shield is affected by your luck stat and at +10 Luck it will activate every time you get hit, Converts all negative pills into their positive counterparts e.g. ?, Satan and The Lamb as Tainted Azazel, When entering a new room, gives a small chance to gain Azazel's short-range Brimstone laser for the current room and the ability to fly, UNLOCK: Unlock this trinket by defeating Mother as Tainted Azazel, Spawns 2 friendly Dips upon clearing a room, Dips that spawn after killing a Squirt turn friendly, UNLOCK: Unlock this trinket by defeating Isaac, ?? * e coli, item room, treasure room, item room pool, tampon, bloody, red, white, red sperm, ecoli, Isaac's tears turn into large scythes that pierce through enemies (Similar to how Death's scythes look), UNLOCK: Unlock this item by beating Challenge #17 (Waka Waka), * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, axe, silver, This page documents some of the more noteworthy item synergies available. - Tears will shoot diagonally for about 60 seconds. ?, Soul of the Lost, 4 rooms: Rune of Ehwaz, Rune of Perthro, Black Rune, Soul of Isaac, Soul of Eve, Soul of Eden, Soul of the Forgotten, Soul of Jacob and Esau, 6 rooms: Rune of Dagaz, Soul of Samson, Soul of Azazel, Soul of Apollyon, Soul of Bethany, 12 rooms: Rune of Jera, Soul of Lilith, Soul of the Keeper, Tears have a chance to fire a fungus tear that sticks to enemies. ?, Keeper and The Forgotten, UNLOCK: Unlock this item by defeating The Beast as Samson, The first time you take damage in a room, Isaac will become a ghost and time will stop for 3 seconds, During this ghost effect, you gain flight, spectral tears and the damage from the next hit you take is negated, Isaac returns to his body if you either clear the room or take damage while in ghost form, Only happens once per room - taking damage a second time does not turn you into a ghost again, UNLOCK: Unlock this item by defeating The Beast as Lazarus, Your tears are replaced with a charge attack that fires a homing, spectral fetus, The fetus tears deal damage equal to 75% of your current tear damage while in contact with enemies, roughly 5 times per second, Can't be held down like normal charge attacks, they will release automatically at full charge, UNLOCK: Unlock this item by defeating The Beast as Lilith, Gives you a familiar that can be charged up to release a black ring, that damages any enemies that touch it with rapid hits (similar to Maw of the Void / Athame effects), The effect does a decent amount of damage, but doesn't scale with your damage upgrades, UNLOCK: Unlock this item by defeating The Beast as Azazel, While firing tears, you now charge up a poop attack for 3 seconds that when released, fires from Isaac's behind, The poop attack deals your current tear damage to any enemies caught in the blast. After a few seconds a huge missile hits the target and deals 20x your tear damage to anything nearby, Essentially a one-time use of the Epic Fetus item, * item room, treasure room, item room pool, grey, gray, robot, Isaac's tears now have a piercing effect which allows them to travel through enemies instead of breaking on hit, * item room, treasure room, item room pool, arrow, penetrative, penetrating shots, grey, gray, There are two different types of items; Active or Passive items. the ability to fly. grey, gray, pentagram, Deals 40 damage to everything in the room when used, REPENTANCE - Reduced to 3 room recharge time, UNLOCK: Unlock this item by using 4 XIII - Death cards, Item Pool: Library, Secret Room, Devil Room, * library pool, library room, book room pool, secret room pool, devil pool, devil room pool, 4 keys = 50% chance. The more you spend the higher the stat increase, Possible stats include Speed, Damage and Range, 15c items give all 3 stats: +1 Damage Up, +0.03 or +0.06 Speed Up, +0.25 or +0.5 Range Up, 5c items give 1 or 2 stats: +0.5 Damage Up **OR** +0.25 Range and +0.03 Speed Up, UNLOCK: Unlock this item by defeating Mother as The Keeper, While in a room with enemies, blue spiders will randomly spawn from objects in the room (e.g. While in a Red room, the chances to spawn a Red Room are: 1 Key = 12.5% chance. For more awesome indie content, subscribe to the channel here and follow me on Twitch for my livestreams!http://www.twitch.tv/pentahybridYou can also join ou. This doesn't work with The Lost characters, While in a room with enemies, red cracks will appear on the floor in random locations, Walking over the crack spawns a white soul familiar, that launches itself into the nearest enemy, exploding and dealing double your tear damage to everything near it, Cracks will keep appearing but only one can exist in the room at a time, UNLOCK: Unlock this item by defeating challenge #38 (Baptism by Fire), While held, this item spawns a familiar that can be moved around using the arrow keys and deals 1.5 damage per tick to any enemies it touches, When activated, you teleport, swapping places with wherever Stitches was positioned, Teleporting next to fires will extinguish them (including blue fires) and on top of shopkeepers will destroy them (gives +10% devil/angel room chance as normal), If used while stitches is on top of an enemy, it can be used to telefrag enemies, dealing x3.5 your damage + 40, Can be used to enter/exit Curse Rooms for free by teleporting infront of the door while holding the direction key to move in immediately. Enemies touching the head don't hurt Isaac, UNLOCK: Unlock this item by defeating Delirium as Tainted Forgotten, Item Pool: Boss Room, Crane Game, Golden Chest, Drops 1 random rune or soul stone when picked up, Item Pool: Shop, Golden Chest, Mom's Chest, Old Chest, Each time you get hit, you drop a coin or two, REPENTANCE - No longer guaranteed to drop coins as The Keeper, UNLOCK: Unlock this item by beating Challenge #15 (Slow Roll), * , the lost item pool, cent, gold, water, wet, blue, While held, Isaac has a significantly higher chance to find drops when breaking poops, Lowers your spacebar item charge rate by 1, Cannot lower the charge of your spacebar item below 1 room, For example, you will now be able to use a 3 room charge item after 2 rooms instead, Does the teleport effect every time you use your current spacebar item, Can be used infinitely every room if you have Guppy's Paw and no red heart containers (Can be exploited to get to the boss room without clearing any other rooms), Higher chance for champion enemies while held, Has a partial Magneto effect and will attract coins, pulling them into Isaac from a distance, Does not attract other pickups like the full Magneto item does, Increases your chances to find an Angel Room instead of a Devil Room, Normally there is a 50%/50% chance of a Angel or Devil room with if a door spawns after the boss.